Early Pulmonary Involvement of Anti-CADM-140 Autoantibody-positive Rapidly Progressive Interstitial Lung Disease Preceding Typical Cutaneous Symptoms
نویسندگان
چکیده
منابع مشابه
Anti-Ro 52 positive dermatomyositis presenting as rapidly progressive interstitial lung disease.
Dermatomyositis is frequently accompanied by interstitial lung disease. This varies greatly in severity, from an asymptomatic imaging finding to a fatal rapidly progressive disease. We present a successfully treated case of rapidly progressive anti-Ro 52 positive dermatomyositis-related interstitial lung disease with accompanying images. A 48-year-old man presented with a 6-week history of dry ...
متن کاملEffective Administration of Rituximab in Anti-MDA5 Antibody–Positive Dermatomyositis with Rapidly Progressive Interstitial Lung Disease and Refractory Cutaneous Involvement: A Case Report and Literature Review
We describe the case of a 48-year-old man with dermatomyositis (DM) who demonstrated rapidly progressive interstitial lung disease (RP-ILD) and refractory cutaneous involvement together with high levels of anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5-Ab). Even after combination immunosuppressive therapy including a corticosteroid, cyclosporine A, and intravenous cyclophos...
متن کاملAnti-CADM-140/MDA5 antibody and clinical subsets of dermatomyositis
The clinical features of dermatomyositis (DM) have a close relationship with myositis-specific antibodies. Clinically amyopathic dermatomyositis (CADM) is a subgroup of DM, which manifests as characteristic skin symptoms compatible with DM, such as Gottron's sign and heliotrope rash with no or mild muscle symptoms. Sometimes, a life-threatening rapidly progressing interstitial lung disease can ...
متن کاملA Case of Sarcoidosis with Interstitial Lung Disease Mimicking Clinically Amyopathic Dermatomyositis and Rapidly Progressive Interstitial Lung Disease
Here, we report a patient with sarcoidosis who developed edematous erythema and interstitial lung disease. At the initial visit, clinically amyopathic dermatomyositis (CADM) with rapidly progressive interstitial lung disease (RP-ILD) was suspected because he had progressive dyspnea but no muscle weakness. The presence of anti-CADM-140/MDA5 autoantibodies was immediately assessed to facilitate a...
متن کاملMyositis autoantibodies in Korean patients with inflammatory myositis: Anti-140-kDa polypeptide antibody is primarily associated with rapidly progressive interstitial lung disease independent of clinically amyopathic dermatomyositis
BACKGROUND To investigate the association between myositis autoantibodies and clinical subsets of inflammatory myositis in Korean patients. METHODS Immunoprecipitation was performed using the sera of classic polymyositis (PM) (n = 11) and dermatomyositis (DM) (n = 38) patients who met the Bohan and Peter criteria for definite inflammatory myositis. A panel of defined myositis autoantibodies w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Internal Medicine
سال: 2014
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.53.2769